Track 15: Gut-Endocrine Axis and Hormonal Regulation– 16th World Probiotics, Nutrition, Gut Health Conference and Exhibition

 Attend the 16th World Probiotics, Nutrition & Gut Health Conference and Exhibition

December 17–19, 2026 | Dubai, UAE

Introduction:

Track 15: Gut-Endocrine Axis and Hormonal Regulation: at the 16th World Probiotics, Nutrition, Gut Health Conference and Exhibition, the spotlight turns toward one of the most fascinating and fast-evolving areas of medical science the Gut–Endocrine Axis.

For decades, hormones were studied mainly through the lens of glands like the pancreas, thyroid, and adrenal system. But emerging research now reveals that the gut microbiome plays a central role in regulating hormonal balance. The trillions of microorganisms residing in the gastrointestinal tract actively communicate with endocrine organs through metabolic, immune, and neural pathways.

This dynamic interaction influences insulin sensitivity, appetite regulation, stress response, thyroid activity, reproductive hormones, and overall metabolic health. Disruptions in gut microbial balance known as dysbiosis are increasingly linked to conditions such as obesity, diabetes, PCOS, thyroid disorders, and chronic stress.

Understanding the gut endocrine connection is not just a scientific breakthrough; it represents a paradigm shift in how we approach hormonal disorders. By targeting the microbiome, clinicians and researchers are opening new pathways for preventive and therapeutic strategies in endocrine health.

What is the Gut–Endocrine Axis?

The Gut–Endocrine Axis refers to the bidirectional communication between the gut microbiota and the endocrine (hormonal) system.

Your gut is not just a digestive organ  it acts as an endocrine organ itself. Gut microbes produce bioactive compounds that influence hormone secretion, metabolism, appetite control, stress response, and reproductive health.

In simple terms:
Your gut bacteria help regulate your hormones  and your hormones influence your gut.

Description

The gut microbiota interacts with endocrine glands through:

·         Microbial metabolites (Short-Chain Fatty Acids – SCFAs)

·         Neuroendocrine signaling pathways

·         Immune system mediators

·         Enteroendocrine cells in the intestinal lining

·         Hypothalamic–pituitary axes

This complex network influences:

·         Insulin production

·         Cortisol levels

·         Thyroid function

·         Estrogen metabolism

·         Appetite hormones (ghrelin & leptin)

Scientific research now shows that gut dysbiosis can disrupt hormonal balance, leading to metabolic and endocrine disorders.

Types of Gut–Endocrine Interactions

1️ Gut–Pancreatic Axis

Impacts insulin secretion and glucose metabolism.

2️ Gut–HPA Axis (Stress Axis)

Microbiota regulate cortisol and stress hormones.

3️ Gut–Thyroid Axis

Gut health influences thyroid hormone conversion and absorption.

4️ Gut–Reproductive Hormone Axis

Bacteria involved in estrogen and androgen metabolism (estrobolome concept).

5️ Gut–Adipose Axis

Regulates leptin, appetite, obesity, and fat storage.

Effects on Health

Disruption in the gut–endocrine axis may contribute to:

·         Obesity

·         Type 2 diabetes

·         PCOS

·         Thyroid dysfunction

·         Chronic stress disorders

·         Metabolic syndrome

·         Infertility

·         Mood disorders

On the positive side, a balanced microbiome can:

✔ Improve insulin sensitivity
✔ Support hormonal balance
✔ Reduce systemic inflammation
✔ Improve metabolic efficiency
✔ Enhance stress resilience

Professionals Involved

This topic is highly relevant for:

·         Endocrinologists

·         Gastroenterologists

·         Nutritionists & Dietitians

·         Functional medicine practitioners

·         Clinical researchers

·         Microbiologists

·         Diabetes specialists

·         Gynecologists

It encourages interdisciplinary collaboration between gut health experts and hormone specialists.

Solving Hormonal Imbalance via the Gut

Emerging strategies include:

·         Probiotic and prebiotic therapy

·         Personalized microbiome modulation

·         Dietary fiber interventions

·         Anti-inflammatory nutrition plans

·         Stress management programs

·         Synbiotic supplementation

·         Precision nutrition approaches

Future therapies aim to target microbiota composition to restore endocrine balance naturally.

 Conclusion

The Gut–Endocrine Axis represents a revolutionary shift in understanding hormonal regulation. Rather than viewing endocrine disorders in isolation, modern science recognizes the gut microbiome as a central regulator of metabolic and hormonal health.

At the 16th World Probiotics, Nutrition, Gut Health Conference and Exhibition, this track will explore cutting-edge research, clinical applications, and innovative probiotic strategies that are redefining endocrine care.

Understanding the gut means understanding hormones. And understanding hormones means unlocking systemic health.

Information:

Conference name: 16th World Probiotics, Nutrition, Gut Health Conference and Exhibition, December 17–19, 2026, in Dubai, UAE
date:
location: Dubai,UAE
registration: https://probiotics-guthealth.utilitarianconferences.com/registration
submit abstract: https://probiotics-guthealth.utilitarianconferences.com/submit-abstract
online registration link